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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT12 All Species: 22.73
Human Site: S377 Identified Species: 45.45
UniProt: Q8IV01 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV01 NP_808878.1 421 46537 S377 V T V A E S S S D G R G D N V
Chimpanzee Pan troglodytes XP_001172576 455 50155 S411 V T V A E S S S D G R G D N V
Rhesus Macaque Macaca mulatta XP_001117977 421 46453 S377 V T V A E S S S D G R G D N V
Dog Lupus familis XP_540824 437 48192 S393 V T V A E S S S D G R G D N V
Cat Felis silvestris
Mouse Mus musculus Q920N7 421 46662 S377 V T V A E S S S D G R G D N V
Rat Rattus norvegicus P97610 421 46590 S377 V T V A E S S S D G R G D N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P47191 424 47487 K369 V T V L D Y D K I G K N D A I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122205 420 46816 E376 V T V A E S T E D G R G E N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 R419 V T V V D Y D R I G T S E P I
Honey Bee Apis mellifera XP_001121685 991 110251 V948 E V S N D Q G V N S K P Y S V
Nematode Worm Caenorhab. elegans P34693 441 49885 K386 I T V M D Y D K L G S N D A I
Sea Urchin Strong. purpuratus XP_784931 322 35947 M279 I T V A Q F G M G G K T P S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 97.3 91.7 N.A. 95 95.9 N.A. N.A. 23.5 N.A. 66.2 N.A. 24.8 21.2 22.6 34.4
Protein Similarity: 100 92.3 98.5 94 N.A. 97.3 97.8 N.A. N.A. 45.2 N.A. 81.4 N.A. 43.2 31.6 45.1 51.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 33.3 N.A. 80 N.A. 26.6 6.6 26.6 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 53.3 N.A. 93.3 N.A. 46.6 33.3 46.6 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 67 0 0 0 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 34 0 25 0 59 0 0 0 67 0 0 % D
% Glu: 9 0 0 0 59 0 0 9 0 0 0 0 17 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 17 0 9 92 0 59 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 0 0 0 0 0 0 17 0 0 0 0 0 25 % I
% Lys: 0 0 0 0 0 0 0 17 0 0 25 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 9 0 0 17 0 59 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 9 9 0 % P
% Gln: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 59 0 0 0 0 % R
% Ser: 0 0 9 0 0 59 50 50 0 9 9 9 0 17 0 % S
% Thr: 0 92 0 0 0 0 9 0 0 0 9 9 0 0 0 % T
% Val: 75 9 92 9 0 0 0 9 0 0 0 0 0 0 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 25 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _